Office 365

Servername: smtp.office365.com

Username: user@domain.com - This username must licenced and exist in office365

Password: <userspassword>

Default From address: from@domain.com - The user must have send privilages over this account in office365

Connection Security: StartTLS

Port: 587

Connection Timeout: 30

add the SMTP server:port as a Generic Endpoint Context server and check the box to validate server certificate. This will also pull in the SMTP server certificate into the trust list.